More Than Hot Flashes: How Menopause Affects the Skin

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Menopause is well known for causing symptoms such as hot flashes and mood swings, but what is talked about much less is the significant effect menopause has on the skin.

So, when women experience increased dryness, laxity, sagging skin, fine lines, wrinkling and dullness, they may not consider that menopause could be at fault.

The good news to share during National Menopause Awareness Month is that there is a solution for women to look their best through all stages of menopause.

How menopause affects the skin
Estrogen is a vital component to maintaining skin health; however, during menopause (and in the years leading up to menopause) estrogen levels naturally decline.1, 2, 3.

This reduction in estrogen can cause dramatic changes in a woman’s facial appearance – often over a short period of time. In fact, low estrogen levels cause greater collagen loss than chronological aging3.

How estrogen helps maintain skin health
Estrogen maintains skin health by stimulating and activating estrogen receptors in two key skin cells: fibroblasts and keratinocytes.

The process encourages fibroblasts to produce collagen, elastin and hyaluronic acid while keratinocytes produce new skin cells, maintaining healthy, vibrant and younger-looking skin 1, 2, 3.

During the first five years of menopause, the decline in estrogen leads to a 30% decrease in dermal collagen. This is the fastest breakdown in collagen and acceleration of intrinsic skin aging that a woman will experience during any stage of her life 2, 3.

Even before menopause, women can notice changes in the appearance of their skin as estrogen levels begin to decline in perimenopause.

What this means
Women want to look their best at every stage of life so it can be frustrating for them to see their skin aging at such a rapid rate.

There is often a lack of education and support for women going through menopause. While they may be able to get help from their general practitioner to tackle other symptoms of menopause, they often don’t make the connection between sudden rapid skin aging and menopause.

“A woman could be doing everything right. She could be using her antioxidants every day, using the appropriate skin care, using daily sun protection, eating a healthy diet, drinking enough water, and she’s still not going to look her best because she’s missing that one factor after menopause. She’s missing that estrogen factor,” says Dr. Diane Berson, an NYC based Dermatologist.

Even though this accelerated skin aging is completely normal, previously there were no skincare solutions to help address the root cause of Estrogen Deficient Skin brought on by perimenopause and menopause.

Introducing Emepelle®
Emepelle® is clinically proven to significantly help improve the visible signs of skin aging brought on by Estrogen Deficient Skin, which occurs during perimenopause and menopause 5. In fact, Emepelle is the only cosmeceutical to feature breakthrough MEP Technology® clinically proven to safely and effectively address the root cause of Estrogen Deficient Skin. Results can be seen in only 8 weeks.

MEP Technology is a new class of cosmeceutical ingredient for mature skin that is innovative and unique. Emepelle with MEP Technology is available in a Serum and Night Cream and can easily be incorporated into a daily regimen. Emepelle Serum contains MEP, antioxidants and niacinamide for daytime use; and Emepelle Night Cream contains MEP, retinol, and peptides for powerful nighttime rejuvenation. When used regularly, Emepelle Serum and Night Cream help reduce skin’s dryness, dullness, thinning, fine lines, and wrinkles.

1. Hall G, Phillips TJ. Estrogen and skin: the effects of estrogen, menopause, and hormone replacement therapy on the skin. J Am Acad Dermatol. 2005;53:555-68.

2. Svoboda RM, DelRosso JQ, Zeichner JA, Draelos ZD. Revisiting the beneficial effects of estrogen on the skin: a comprehensive review of the literature and a look to the future. Skin. 2018;2:308-16.

3. Archer DF. Postmenopausal skin and estrogen. Gynecol Endocrinol. 2012;28 (suppl 2):2-6. Doi:10.3109/09513590.2012.705392.

4. Draelos ZD. A double-blind randomized pilot study evaluating the safety and efficacy of topical MEP in the facial appearance improvement of estrogen deficient females. J Drugs Dermatol. 2018;17(11):1032-1035.

5. Rzepecki AK, Murase JE, Rupal J, Fabi SG, McLellan BN. Estrogen-deficient skin: The role of topical therapy. Intl. J. Women’s Dermatol. 2019;5:85-90

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